NSAIDS









The abbreviation NSAIDS stands for non-steroidal anti-inflammatory drugs. They’re a class of medication that has analgesic (pain relieving) and anti-inflammatory properties, which reduce inflammation and swelling. Aspirin (Acetylsalicylic Acid or ASA) was the first drug in this class. It was patented in 1899 by Bayer. Ibuprofen in a 200mg strength and naproxen sodium in a 220mg strength are two other over-the-counter drugs in this class that are available without a prescription.



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Other non-steroidal anti-inflammatory drugs require a prescription. The newest class of non-steroidal anti-inflammatory drugs is called Cox-2 inhibitor. This class was said to cause less stomach problems than the original class when it first came out. However, the FDA re-evaluated the cox-2s after reports of heart attack and stroke and one drug was withdrawn from the market.



NSAIDs That Need a Prescription



Generic Name * Trade name

Celecoxib * Celebrex

Diclofenac * Flector, Cataflam, Volteren, Arthrotec (combined with misoprostol)

Diflunisal * Dolobid

Etodolac * Lodine, Lodine XL

Fenoprofen * Nalfon, Nalfon 200

Flurbiprofen * Ansaid

Ibuprofen * Motrin, Tab-Profen, Vicoprofen (combined with hydrocodone), Combunox (combined with oxycodone)

Indomethacin * Indocin, Indocin SR, Indo-Lemmon, Indomethgen

Ketoprofen * Oruvail

Ketorolac * Toradol

Mefenamic Acid * Ponstel

Meloxicam * Mobic

Nabumetone * Relafen

Naproxen * Naprosyn, Anaprox(sodium), Anaprox DS, EC-Naprosyn, Naprelan

Oxaprozin * Daypro

Piroxicam * Feldene

Sulindac * Clinoril

Tolmetin * Tolectin Tolectin DS, Tolectin 600


Over the counter non-steroidal anti-inflammatory drugs now contain a label that warns that long term continuous use may increase the risk of heart attack or stroke. Prescription NSAIDS require that a medication guide be given out when the prescription is dispensed. This guide states that these medication my increase the chance of a heart attack or stroke that can lead to death. It also lists other important information for the patient including possible side effects.

Serious side effects include: heart attack, stroke, high blood pressure, heart failure from body swelling (fluid retention), kidney problems including kidney failure, bleeding and ulcers in the stomach and intestine, low red blood cells (anemia), life-threatening skin reactions, life-threatening allergic reactions, liver problems including liver failure, and asthma attacks in people who have asthma. Other side effects include: stomach pain, constipation, diarrhea, gas, heartburn, nausea, vomiting, and dizziness.

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