Premenstrual Syndrome

Neptune Krill oil, and its effects on premenstrual syndrome, or PMS, is the first major clinical study done on the oil.

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In 2002, physicians at the University of Montreal, McGill University, and other medical centers in Quebec conducted a randomized, double-blind study about the use of krill oil for relieving premenstrual syndrome symptoms. It was published in 2005 in the Alternative Medicine Review (Volume 8, Number 2).

The three-month clinical study found that krill oil dramatically improved both the physical and emotional symptoms of PMS and dysmenorrhea, painful or difficult menstruation.

Effects of Neptune Krill Oil on PMS

• Relieves bloating, nausea, and fatigue

• Eases uterine cramps and abdominal pain

• Lessens breast tenderness

• Alleviates headache, and joint and body aches

• Improves erratic mood swings and food cravings

• Helps prevent episodes of anxiety, depression, and stress related to menses


• OTC and prescription pain relievers

• Diuretics

• Synthetic hormones

• Antidepressants

• Change in diet

• Exercise

• Stress-reduction

• Sleep

Women are now turning to alternative or natural remedies for PMS relief. Omega-3 fatty acids are among the most effective nutritional therapies, according to numerous studies. Natural progesterone cream is another affective natural remedy.

Some experts believe that premenstrual syndrome might stem from an imbalance of the female hormones estrogen and progesterone during the second half of the menstrual cycle, after ovulation. Too little progesterone and too much estrogen limit the production of certain neurotransmitters that control inflammation-related pain and mood. The fatty acids EPA and DHA in the omega-3s have potent anti-inflammatory properties, which help ease PMS symptoms of headaches, cramps, bloating, and nausea and vomiting.

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PMS Symptoms Reduced by Neptune Krill Oil

Symptom - % reduction

• Joint pain - 64%

• Irritable - 47%

• Overwhelmed - 42%

• Breast tenderness - 42%

• Depression - 40%

• Stress - 38%

• Swelling - 37%

• Abdominal pain - 33%

• Weight gain - 30%

• Bloating - 21%

The Krill Oil Study

The researchers used 70 otherwise healthy volunteers whose symptoms met the standardized diagnostic criteria for PMS. The women were assigned randomly into one of two groups. 36 women received Neptune krill oil and 34 received fish oil (the control).

The women in the Neptune krill oil group reported remarkable improvement in 10 out of 10 categories, both physical and emotional.

Krill oil group - - - - - - Fish oil group

• Less weight gain - - - Less weight gain

• Less abdominal discomfort - - Less abdominal discomfort

• Less swelling - - - - - - Less swelling

• Less breast tenderness

• Less anxiety

• Less irritability

• Less depression

• Less joint discomfort

• Less bloating

• Less feelings of inadequacy


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The information on is not offered for the diagnosis, cure, mitigation, treatment, or prevention of any disease or disorder nor have any statements herein been evaluated by the Food and Drug Administration (FDA). We strongly encourage you to discuss topics of concern with your health care provider.

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